All the Same? The Secret Life of Prion Strains within Their Target Cells
Prions are infectious β-sheet-rich protein aggregates composed of misfolded prion protein (PrPSc) that do not possess coding nucleic Suspension Stabilizer Bar Quick Disconnect acid.Prions replicate by recruiting and converting normal cellular PrPC into infectious isoforms.In the same host species, prion strains target distinct brain regions an